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Advantage Multi Cat

Bayer Animal health

$22.38 - $175.22


$22.38 Each

Advantage Multi® for Cats

Advantage Multi® for Cats is a convenient, broad-spectrum heartworm preventive in a monthly topical application. It is also indicated to kill adult fleas and treat flea infestations, as well as to treat and control roundworm infections caused by Toxocara cati, hookworm infections caused by Ancylostoma tubaeforme, and ear mite infestations caused by Otodectes cynotis. Advantage Multi for Cats is for use on cats and kittens at least 9 weeks of age and weighing at least 2 lbs. Advantage Multi® for Cats (orange label) can also be used on ferrets that weigh at least 2 lbs.

Key Benefits:

  • 100% effective in the prevention of heartworm disease as shown in clinical trials
  • Flea-killing power of imidacloprid, the same active ingredient as in Advantage® Topical Solution
  • Treatment and control of roundworms and hookworms as early as L4 stage, while most dewormers purge only adult-stage intestinal parasites
  • Treats ear mites with a single dose. Monthly use will control subsequent infestations.
  • Topical drops are less stressful for pet owners than giving their cat a pill or tablet
  • The only FDA-approved product indicated for ferrets for the treatment of fleas and prevention of heartworm disease

Why choose Advantage Multi® for your cat?


An icon of group of parasites.
Help protect your cat from multiple parasites, inside and out — all in one convenient monthly application.
An icon of antibiotics within a no symbol.
Easy-to-use, monthly topical application — no pill required
An icon of a dead flea.
Kills fleas through contact, so they don’t have to bite your cat to die
An icon of a mite.
Treats ear mites, the No. 1 cause of ear infections in cats

The recommended minimum dose is 4.5 mg/lb (10.0 mg/kg) imidacloprid and 0.45 mg/lb (1.0 mg/kg) moxidectin, once a month, by topical administration. Do not apply to irritated skin.

    1. Remove one dose applicator tube (tube) from the package. As specified in the following table, administer the entire contents of the Advantage Multi® for Cats tube that correctly corresponds with the body weight of the cat.
Cat (lbs.) Advantage Multi for Cats Volume (mL) Imidacloprid (mg) Moxidectin (mg)
2-5 Advantage Multi 5 0.23 23 2.3
5.1-9 Advantage Multi 9 0.4 40 4
2.0-4.4 lbs
Advantage Multi 9 0.4 40 4
9.1-18* Advantage Multi 18 0.8 80 8
      *Cats over 18 lbs. should be treated with the appropriate combination of Advantage Multi for Cats tubes.

  1. While holding the tube in an upright position, remove the cap from the tube.
  2. Turn the cap over and push the other end of cap onto the tip of the tube.
  3. Twist the cap to break the seal and then remove cap from the tube.
  4. Part the hair on the back of the cat's/ferret's neck at the base of the head, until the skin is visible. Place the tip of the tube on the skin and apply the entire contents directly on the exposed skin. Lift tube away from skin before releasing pressure on tube.


Do not get this product in the animal's mouth or eyes or allow the cat to lick the application site for 30 minutes. Treatment at the base of the head will minimize the opportunity for ingestion by grooming. In households with multiple pets, keep animals separated to prevent licking of the application site.

Stiff, matted hair or a damp, oily appearance of the hair may be observed at the application site on some animals. This is temporary and does not affect the safety and effectiveness of the product.

Heartworm Prevention: For prevention of heartworm disease, Advantage Multi® for Cats should be administered at one-month intervals. Advantage Multi® for Cats may be administered year-around or at a minimum should start one month before the first expected exposure to mosquitoes and should continue at monthly intervals until one month after the last exposure to mosquitoes. If a dose is missed and a 30-day interval between doses is exceeded, administer Advantage Multi for Cats immediately and resume the monthly dosing schedule. When replacing another heartworm preventative product in a heartworm prevention program, the first treatment with Advantage Multi® for Cats should be given within one month of the last dose of the former medication. At the discretion of the veterinarian, cats older than 6 months of age may be tested to determine the presence of existing heartworm infection before treatment with Advantage Multi for Cats (See ADVERSE REACTIONS - Foreign Market Experience).

Flea Treatment: For the treatment of flea infestations, Advantage Multi for Cats should be administered at one-month intervals. If the cat is already infested with fleas when the first dose of Advantage Multi for Cats is administered, adult fleas on the cat will be killed. However, re-infestation from the emergence of pre-existing pupae in the environment may continue to occur for six weeks or longer after treatment is initiated. Cats treated with imidacloprid, including those with pre-existing flea allergy dermatitis have shown clinical improvement as a direct result of elimination of fleas from the cat.

Ear Mite Treatment: For the treatment of ear mites (Otodectes cynotis), Advantage Multi for Cats should be administered once as a single topical dose. Monthly use of Advantage Multi for Cats will control any subsequent ear mite infestations.

Intestinal Nematode Treatment: For the treatment and control of intestinal hookworm infections caused by Ancylostoma tubaeforme (adults, immature adults and fourth stage larvae) and roundworm infections caused by Toxocara cati (adults and fourth stage larvae), Advantage Multi for Cats should be administered once as a single topical dose.

Not for human use.
Keep out of reach of children.
Children should not come in contact with the application site for 30 minutes after application.
Causes eye irritation. Harmful if swallowed. Do not get in eyes or on clothing. Avoid contact with skin. Wash hands thoroughly with soap and warm water after handling.
If contact with eyes occurs hold eyelids open and flush with copious amounts of water for 15 minutes. If eye irritation develops or persists, contact a physician.
If swallowed, call poison control center or physician immediately for treatment advice. Have person sip a glass of water if able to swallow. Do not induce vomiting unless told to do so by the poison control center or physician.
People with known hypersensitivity to benzyl alcohol, moxidectin, or imidacloprid should administer the product with caution. In case of allergic reaction, contact a physician.
If contact with skin or clothing occurs, take off contaminated clothing. Wash skin immediately with plenty of soap and water. Call a poison control center or physician for treatment advice. The Material Safety Data Sheet (MSDS) provides additional occupational safety information.

WARNINGS: Do not use on sick, debilitated, or underweight cats. Do not use on cats less than 9 weeks of age or less than 2 lbs of body weight.

Do not dispense dose applicator tubes without complete safety and administration information.
Avoid oral ingestion. Cats may experience hypersalivation, tremors, vomiting and decreased appetite if Advantage Multi® for Cats is inadvertently administered orally or through grooming/licking of the application site.
The safety of Advantage Multi® for Cats has not been established in breeding, pregnant, or lactating cats.
Use of this product in geriatric patients with subclinical conditions has not been adequately studied. Several otherwise healthy, thin geriatric cats experienced prolonged lethargy and sleepiness after using this drug.


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